Cancer Treatment Today » relapsed http://cancertreatmenttoday.org Knowledge is Power Thu, 26 Mar 2026 23:39:25 +0000 en-US hourly 1 Zolinza for Hodgkin’s http://cancertreatmenttoday.org/zolinza-for-hodgkins/ http://cancertreatmenttoday.org/zolinza-for-hodgkins/#comments Fri, 01 Mar 2013 21:03:38 +0000 M Levin, MD http://cancertreatmenttoday.org/?p=10805 Current chemotherapy drugs are very effective for Hodgkin’s  lymphomas but patients who relapse after receiving them don;t do as well. This is because the cancers develop resistance to the se drugs. Zolinza is a new drug approved in the USA for the treatment of cutaneous(skin) T-cell lymphoma who have progressive, persistent or recurrent disease  or following two systemic therapies. It may be effective for Hodgkin’s. For Hodgkin’s, a phase II study enrolled twenty-five eligible patients. The overall resposne rate was low, 4% (one partial response), but the drug was well tolerated. A phase I clinical trial treated several types of lymphoma. The best responses were seen in those with Hodgkin and diffuse large B-cell lymphoma (Budde et al). A study of Vorinostat and Lenalidomide in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma or Non-Hodgkin Lymphoma was started at the City of Hope but was terminated.

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