Cancer Treatment Today » targeted drugs http://cancertreatmenttoday.org Knowledge is Power Thu, 21 May 2026 12:55:14 +0000 en-US hourly 1 Iclusig (ponatinib) http://cancertreatmenttoday.org/inclusing-ponatinib/ http://cancertreatmenttoday.org/inclusing-ponatinib/#comments Thu, 28 Feb 2013 17:50:24 +0000 M Levin, MD http://cancertreatmenttoday.org/?p=10790 Ponatinib (Iclusig, AP24534) was recently FDA approved for the treatment of chronic myeloid leukemia (CML) and Philadelphia chromosome positive (Ph+) acute lymphoblastic leukemia (ALL). It was approved based on the inital results of The PACE (Ponatinb Ph+ ALL and CML Evaluation) trial. B ecasue it not only attacks the CML mutation, BCR-ABL (including the T315I that other drugs doen affect it is an attarctive candidate for personalized use in conditions that display these mutations in the Personalized Medicine approach.

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Personalized Medicine

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