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Primary sclerosing cholangitis (PSC) is a chronic, liver disease characterized by bile stasis within bile ducts and liver inflammation and fibrosis. It is thought to be an immune mediated, progressive disorder that eventually develops into liver cirrhosis, portal hypertension and hepatic decompensation, in the majority of patients. How does one follow the activity of this disease? Guidelines do not recommend routine MRCP or ERCP to screen for screening

Primary sclerosing cholangitis (PSC) is a chronic, cholestatic liver disease characterized by inflammation and fibrosis of both intrahepatic and extrahepatic bile ducts. It is thoughtto be an immune mediated, progressive disorder that eventually develops into cirrhosis, portal hypertension and hepatic decompensation, in the majority of patients. Guidelines do not recommend routine MRCP or ERCP to screen for chalngiocarcinoma or hepatocellular carcinoma.