Systemic Therapy for Desmoid Tumors – pro

Desmoid tumors (also called aggressive fibromatosis, deep musculoaponeurotic fibromatosis, and fibrosarcoma grade I of the desmoid type) are locally aggressive tumors with no known potential for metastasis or dedifferentiation. However, tumor invasion into vital structures and/or organs can result in substantial morbidity and may be fatal. Local control using surgery and radiation has traditionally been the mainstay of therapy for these tumors but

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