Biological Therapies

Chemo Options for Later Lines of Therapy for Metastatic Colon Cancer

There are now five different classes of drugs with significant antitumor activity in colon cancer: Fluoropyrimidine(5-fluorouracil [5-FU] which is usually given with leucovorin [LV], capecitabine, tegafur plus uracil [UFT]), Irinotecan, Oxaliplatin, Cetuximab and panitumumab (Vectbix). The latter two are monoclonal antibodies (MoAbs) directed against the epidermal growth factor receptor (EGFR), and bevacizumab, is a monoclonal antibody targeting

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