Less Common Lymphomas

Double Hit Lymphoma

Double - hit (DH) lymphomas are a recently discovered subtype of lymphoma that is defined by a chromosomal breakpoint affecting the MYC/8q24 locus in combination with another recurrent breakpoint, for instance a t(14;18)(q32;q21), involving BCL2. In the 2008 WHO classification, they are classified as "B cell lymphoma unclassifiable with features intermediate between Diffuse Large Cell Lymphoma(DLBCL) and Brkitt’s Lymphoma(BL)". Thus, it is somewhere

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Adjuvant Therapy for Early-Stage Marginal Zone Lymphoma

Extranodal marginal zone lymphoma, also called low grade B-cell lymphoma of mucosa-associated lymphoid tissue (MALT), is a lymphoma that, unlike most other lymphomas, arises outside of lymph nodes, in a number of locations, including the stomach, salivary glands, lung and small intestine. There is evidence for marginal zone lymphoma in general that it might be disseminated at presentation. Therefore, it is tempting to prescribe adjuvant chemotherapy

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