Cancer Treatment Today

Among the reffects of Snadostatin is  reduction of blood flow to the Go tract, and inhibition of release of several gastrointestinal hormones, which might decrease leaking from fistulas after surgery and help them heal. Several studies and a meta-analysis looked at this effect.  UNfortunately, the results are mixed and not entirely convincing. A recent Cochrane review of somatostatin analogues (SSAs) for pancreatic surgery concluded that SSAs reduce

The principal effects of octreotide include inhibition of growth hormone (GH), glucagon, and insulin. However, there are other effects that have been attemtped to be exploited to therapeutic ends, including to help heal pancreatic and gastreointeistinal fistulas.  Among themare reduction of splanchnic blood flow, and inhibition of release of several gastrointestinal hormones, including serotonin, gastrin, vasoactive intestinal peptide, secretin,