Allogeneic Transplantation for Chronic Neutrophilic Leukemia – pro
Chronic Neutrophilic LeukemiaCNL( is classified as a Myeloproliferative Disoder(MPD). It is rare. When finally defined as a distinct disease by the World Health Organization in 2004, only 150 cases had been reported. Although similar to CML, a condition for which allogeneic transplantation is well established, it is a different disease and stem cell transplantation had not been adequately studied. Only a few case reprots with varying outcomes have been reported.
Piliotis E, Kutas G, Lipton JH (2002) Allogeneic bone marrow transplantation in the management of chronic neutrophilic leukemia. Leuk Lymphoma 43: 2051- 2054.
Goto H, Hara T, Tsurumi H, Tanabashi S, Moriwaki H (2009) Chronic neutrophilic leukemia with congenital Robertsonian translocation successfully treated with allogeneic bone marrow transplantation in a young man. Intern Med 48: 563- 567.
Piliotis E, Kutas G, Lipton JH. Allogeneic bone marrow transplantation in the management of chronic neutrophilic leukemia. Leuk Lymphoma. 2002 Oct;43(10):2051-4.
A Tefferi et al, Classification and diagnosis of myeloproliferative neoplasms: The 2008 World Health Organization criteria and point-of-care diagnostic algorithms Leukemia (2008), 14-22