CA-125 for workup of adnexal mass – pro

A woman with a pelvic mass can present a difficult dilemma for the gynecologic surgeon because of the uncertainty about whether she should be referred for specialty surgical care. If the mass proves to be malignant, it will typically require an extensive operation, including formal staging, which is best performed by a gynecologic oncologist. Specific referral guidelines have been recommended jointly by the SGO and ACOG to help guide the generalist in deciding whom to operate and whom to refer. The usefulness of these guidelines in distinguishing benign from malignant masses, has been confirmed by retropsective review, especially in more advanced disease stages. CA-125 is an important part of the workup for suspicious adnexal massess.

J.E. Dodge wt al, Practice Guideline Series, Management of a suspicious adnexal mass: a clinical practice guideline, OncologyVol 19, No 4 (2012)

Michael P. Stany1, G. Larry Maxwell and G. Scott Rose   Women’s Imaging Review: Clinical Decision Making Using Ovarian Cancer Risk AssessmentAJR February 2010, Volume 194, Number 2,

Samuel S et al, .Validation of Referral Guidelines for Women With Pelvic Masses
Obstetrics & Gynecology 2005;105:35-41

Amy C. Dearking et al, How Relevant Are ACOG and SGO Guidelines for Referral of Adnexal Mass?Obstetrics & Gynecology 2007;110:841-848

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