Colorectal small cell carcinoma (RESCC) is a rare tumor with an aggressive course. Only case reports exist to guide surveillance approach.Most cases of small cell cancers of organs other than ung are trated as if they were metastatic small cell lung cancer. A recent stuedy showed that of 120 patients with ESCC, in which the most frequent site of origin was the female genital tract (26 percent), followed by gastrointestinal tract (23 percent), genitourinary tract (19 percent), head and neck (16 percent), unknown primary site (13 percent), and other sites (4.3 percent). The repovailing approach of treating extrapulmonary small cell cancers as small cell lung cancer has been questioned and treatmnen results in general are poor. There are no guidelines or reviews that recommend routine surveillance for patients with colonic EPCCC.
Dina El Demellawy et al, Primary colorectal small cell carcinoma: A clinicopathological and immunohistochemical study of 10 cases Diagnostic Pathology 2007, 2:35
Brennan SM, Gregory DL, Stillie A, et al. Should extrapulmonary small cell cancer be managed like small cell lung cancer? Cancer 2010; 116:888.
Ochsenreither S, Marnitz-Schultze S, Schneider A, et al. Extrapulmonary small cell carcinoma (EPSCC): 10 years’ multi-disciplinary experience at Charité. Anticancer Res 2009; 29:3411.
Wong YN, Jack RH, Mak V, et al. The epidemiology and survival of extrapulmonary small cell carcinoma in South East England, 1970-2004. BMC Cancer 2009; 9:209.
Walenkamp AM, Sonke GS, Sleijfer DT. Clinical and therapeutic aspects of extrapulmonary small cell carcinoma. Cancer Treat Rev 2009; 35:228.
Jonathan R. Strosberg,The NANETS Consensus Guidelines for the Diagnosis and Management of Poorly Differentiated (High-Grade) Extrapulmonary Neuroendocrine Carcinomas Pancreas. 2010 August; 39(6): 799–800.
Cicin I, Karagol H, Uzunoglu S, Uygun K, Usta U, Kocak Z, Caloglu M, Saynak M, Tokatli F, Uzal C.
Extrapulmonary small-cell carcinoma compared with small-cell lung carcinoma: a retrospective single-center study. Cancer. 2007 Sep 1;110(5):1068-76.