Hepatoblastoma is a rare pediatric cancer that can be cured by surgery. Preoperative chemotherapy followed by complete surgical excision according to International Society of Paediatric Oncology guidelines yields excellent results with a current survival rate of 80%.Liver transplantation is a curative option as well.Various chemotherapy regimens have been reported but there are no prospective studies and no studies of second line chemotherapy. Czauderna P, Otte JB, Aronson DC, Gauthier F, Mackinlay G, Roebuck D, Plaschkes J, Perilongo G; Childhood Liver Tumour Strategy Group of the International Society of Paediatric Oncology (SIOPEL).Guidelines for surgical treatment of hepatoblastoma in the modern era–recommendations from the Childhood Liver Tumour Strategy Group of the International Society of Paediatric Oncology (SIOPEL).Eur J Cancer. 2005 May;41(7):1031-6.
Davies JQ, de la Hall PM, Kaschula RO, Sinclair-Smith CC, Hartley P, Rode H, Millar AJ.Hepatoblastoma–evolution of management and outcome and significance of histology of the resected tumor. A 31-year experience with 40 cases.J Pediatr Surg. 2004 Sep;39(9):1321-7.
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