High-intensity focused ultrasound uses ultrasound (high-energy sound waves) to destroy prostate cancer cells. An endorectal probe is used to make the sound waves. Unfortunately, there are no randomized controlled trials or meta-analyses comparing HIFU with currently accepted management approaches and evidence is primarily based on data from case series. The National Institute for Health and Clinical Excellence (NICE) has issued full guidance to the NHS in England, Wales, Scotland and Northern Ireland on high-intensity focused ultrasound for prostate cancer in March 2005 and reaffirmed in 2008: ” High intensity focused ultrasound (HIFU) and cryotherapy are not recommended for men with localised prostate cancer other than in the context of controlled clinical trials comparing their use with established interventions.” Cancer Care Ontraio in 2010 says that HIFU is currently not recommended as an alternative to accepted curative treatment approaches for localized prostate cancer.
http://dx.doi.org/10.1155/2012/960835Clinical StudyHigh-Intensity Focused Ultrasound for Prostate Cancer: Francesco Ziglioli, Long-Term Followup and Complications RateUmberto Maestroni, Francesco Dinale, Roberto Minari, Paolo Salsi, and Advances in Urology, Volume 2012 (2012).
Himu Lukka et al, High-intensity focused ultrasound for prostate cancer: a practice guideline Can Urol Assoc J. 2010 August; 4(4): 232–236.
Blana A, Brown SCW, Chaussy C, Conti GN, Eastham JA, Ganzer R, Murat FJ, Pasticier G, Rebillard X, Rewcastle JC, Robertson CN, Thuroff S, Ward JF.High-intensity focused ultrasound for prostate cancer: comparative definitions of biochemical failure. BJUI, 2009; 104, 1058-1062