Humira for sarcoidosis – pro

Humira is a drug similar to Remicaid. It is potentially effective in sarcoidosis but there is not much supporting evidence. There are several case reports but I could not find prospective studies. A study was planned but suspended prior to enrollment: Efficacy Study of Humira in the Treatment of Cutaneous Sarcoidosis, NCT00731757
Trial of Adalimumab in Progressive Sarcoidosis NCT00311246
was terminated due to difficulty in recruiting. Two other trials for cutaneous sarcoidosis are listed on the site. Humira for sarcoidosis is a potentially efective but not literature supported treatment at this time.

A.-M. Thielen, C. Barde, J.-H. Saurat, E. Laffitte
Refractory Chronic Cutaneous Sarcoidosis Responsive to Dose Escalation of TNF-Alpha Antagonists Dermatology Vol. 219, No. 1, 2009

Michael P. Heffernan, MD; David I. Smith, MD
Adalimumab for Treatment of Cutaneous Sarcoidosis Arch Dermatol. 2006;142:17-19.

Gupta et al. Treatment of sarcoid granulomatous interstitial nephritis with adalimumab
NDT Plus 2009;2:139-142.

 Rivkina AM, Stump LS. Infliximab in graft-versus-host disease. Am J Health-Syst Pharm 2002;59(13):1271-1275.

 Ball LM, Egeler RM. Acute GvHD: pathogenesis and classification. Bone Marrow Transplant. Jun 2008;41 Suppl 2:S58-64.

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