IVIG for Aplastic Anemia – pro
Aplastic Anemia is considered to be among the diseases for which the Plan considers IVIG to experimental. Unfortunately there is very little supporting literature. A 2007 review found 7 reported cases, all of which responded to IVIG, but upon a closer look the review authors found that only 2 of the cases met criteria for true Aplastic Anemia. A 2007 guideliens (Anderson et al) concluded that : “There is no evidence to support the use of IVIG in aplastic anemia”.
D . Anderson , K . Ali , V . Blanchette , M . Brouwers , S . Couban , P . Radmoor , L . Huebsch , H . Hume , A . McLeod , R . Meyer Guidelines on the Use of Intravenous Immune Globulin for Hematologic Conditions . Transfusion Medicine Reviews , Volume 21 , Pages S9 – S56 2007
Munehiro Honda, ISRN EndocrinologyVolume 2011 (2011), Successful Treatment of Methimazole-Induced Severe Aplastic Anemia by Granulocyte Colony-Stimulating Factor, Methylprednisolone, and Cyclosporin