Metastatic basal cell carcinomais very rare. THE REPORTED incidence of metastatic basal cell carcinoma (MBCC) ranges from 0.003% to 0.55%. The range is in part due to the lack of accurate data for the incidence of basal cell carcinoma (BCC), which has an estimated incidence of 900 000 to 1 200 000 in the United States, but is excluded from traditional national cancer registries, such as Surveillance, Epidemiology and End Results. While BCC is a slow-growing, usually nonmetastazing but invasive tumor, at least 230 cases fulfilling the criteria for metastatic basal cell (MBCC) were reported in the literature. Metastasis to regional nodes or lungs occurred in long-standing recurrent lesions. There is little secure experience with treatment modalilities and chemotherapy must be considered experimental.
G. R. Mikhail; L. P. Nims; A. P. Kelly, Jr; D. M. Ditmars, Jr; W. R. Eyler
Metastatic basal cell carcinoma: review, pathogenesis, and report of two cases
Arch Dermatol. 1977;113(9):1261-1269.
June K. Robinson; Madhu Dahiya
Basal Cell Carcinoma With Pulmonary and Lymph Node Metastasis Causing Death
Arch Dermatol. 2003;139(5):643-648.