1.Does the patient meet medical necessity for the proposed use of Herceptin for muscionus HER- breast carcinoma?
2.Is it appropriate in the amount, duration and frequency of care and consistent with the symptoma or diagnosis?
3.Is it appropriate with regard to widely accepted standards?
4.Is it mainly for convenience?
5.Is ithe procedure the least costly option…?
6. Do the servoces constitute accepted medical practice…?
7.Was informed consent utilized or procedure reviewed by IRB?
7b.Does Federal Law require such approval?
8.Does reliable evidence indicate that it is subject to on-going phase I, II clinical trials, is the research arm of phase III trial, or otherwise under study…?
9.Does reliable evidence show that the prevailing opinon among experts is that farther studies are necessary…?