When cervical cancer recurrs after chemoradiation, options are limited and include surgical exenteration, chemotherapy of reirradiation. The latter option is not well studied.Several case series have been published but the results have not been impressive. Whether IMRT, hyperfractionated radiation or confomrmal modlalities are useful is not known. The role of radioprotectants, such as Amifostine, has not been studied.
Kim JH, Choi TJ, Kim OB.Reirradiation in Rcurrent Cervical Cancer Following Definite Radiation Therapy. J Korean Soc Ther Radiol Oncol. 2001 Sep;19(3):230-236.