18F-Fluoride is a different kind of PET scan, which uses sodium fluoride instead of technetium. It is more PET avid than FDG PET. Society of Nuclear Medicine says this: ” No appropriateness criteria have been developed to date for this procedure. PET/CT 18F bone scans may be used to identify skeletal metastases, including localization and determination of the extent of disease. Insufficient information exists to recommend the following indications in all patients, but may be appropriate in certain individuals…..”
http://www.snm.org/docs/Practice%20Guideline%20NaF%20PET%20V1.1.pdf
National Health and Medical Research Council (Australia). A systematic review of the efficacy and safety of fluoridation [PDF]. 2007. ISBN 1-86496-415-4. Summary: Yeung CA. A systematic review of the efficacy and safety of fluoridation. Evid Based Dent. 2008;9(2):39–43. doi:10.1038/sj.ebd.6400578. PMID 18584000. Lay summary: NHMRC, 2007.
de Arcocha M, Portilla-Quattrociocchi H, Medina-Quiroz P, Carril JM.
Current status of the use of 18F-sodium fluoride in bone disease.
Rev Esp Med Nucl. 2012 Jan-Feb;31(1):51-7. Epub 2011 Jul 26.