Treatment of Sclerosing Mesenteritis – pro

Sclerosing mesenteritis, also called mesenteric panniculitis, is a rare non-neoplastic disease that affects the small bowel mesentery with chronic fibrosing inflammation. Although a relatively benign condition, sclerosing mesenteritis can have a prolonged debilitating course with a fatal outcomeThere are few data on the natural history and therapeutic options for this condition. Tamoxifen in combination with prednisone is teh most common treatment, and most patients respond. I did not find any reports of the use of Rituxan.

Savvas Hiridis et al, Sclerosing mesenteritis affecting the small and the large intestine in a male patient with non-Hodgkin lymphoma: a case presentation and review of the literature
Journal of Medical Case Reports 2008, 2:388

Sclerosing mesenteritis: clinical features, treatment, and outcome in ninety-two patients.
Clin Gastroenterol Hepatol. 2007 May;5(5):589-96.
Pemberton, John D, Idiopathic Sclerosing Orbital Inflammation: A Review of Demographics, Clinical Presentation, Imaging, Pathology, Treatment, and Outcome Ophthalmic Plastic & Reconstructive Surgery: January/February 2012 – Volume 28 – Issue 1 – p 79–83

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