Methylnatrexone (Movantik) for pruritis – pro
Methylnatrexone is recently identified as being helpful in managing pruritis from opiods as well as pruritis from other causes. British Society of Dermatology recommends it a a 4tht line drug.It says: ” Naltrexone or nalmefene are considered fourth‐line treatments (Strength of recommendation D (GPP); Level of evidence 4)”.
G.W.M. Millington et al, British Association of Dermatologists’ guidelines for the investigation and management of generalized pruritus in adults without an underlying dermatosis, BJD Volume178, Issue1, January 2018, Pages 34-602018
Movantik Prescribing Information 2018
Peter Deibert et al, Methylnaltrexone: the evidence for its use in the management of opioid-induced constipation. Core Evid. 2009; 4: 247–258.