Carboplatin is not a very nephrotoxic drugs, and hydration si nto standard; kidney function is good.Oral hydration should suffice. For carboplatin, hydration is important for patients with impaired renal function and for patients receiving high doses of drug (> or = 800 mg/m2). Cornelison et al, writes: “For carboplatin, hydration is important for patients with impaired renal function and for patients receiving high doses of drug (> or = 800 mg/m2). “Carboplatin is not a very nephrotoxic drugs, and hydration si nto standard; kidney function is good.Oral hydration should suffice. For carboplatin, hydration is important for patients with impaired renal function and for patients receiving high doses of drug (> or = 800 mg/m2). Cornelison et al, writes: “For carboplatin, hydration is important for patients with impaired renal function and for patients receiving high doses of drug (> or = 800 mg/m2). ”
Cornelison TL, Reed E. Nephrotoxicity and hydration management for cisplatin, carboplatin, and ormaplatin. Gynecol Oncol. 1993 Aug;50(2):147-58
Sleijfer DT, Smit EF, Meijer S, Mulder NH, Postmus PE. Acute and cumulative effects of carboplatin on renal function. Br J Cancer. 1989 Jul;60(1):116-20.
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