“ An MMWR study suggests that pregnant women with COVID-19 are more likely to be hospitalized and are at increased risk for intensive care unit (ICU) admission and receipt of mechanical ventilation than non-pregnant women. Risk of death is similar for both groups. But much remains unknown.”

Just reported is a meta-analysis that conclude: “In comparison to non-pregnant women with COVID-19, pregnant women with the disease had higher odds of admission to the intensive care unit (1.62, 95% PI 1.33-1.96) and need for invasive ventilation (1.88, 1.36-2.60). A pre-existing maternal comorbidity further increased  odds of requiring intensive care (4.21, 1.06-16.72) and for invasive ventilation (4.48, 1.40-14.37).

Pregnant women with COVID-19 had an overall preterm birth rate of 17% (13-21), and 6% (3-9) rate of spontaneous preterm births. The odds of any preterm birth were higher with COVID-19 than without (3.0, 1.15-7.85). There were no statistically significant differences in other maternal outcomes between those with or without COVID-19; or in neonatal outcomes, other than neonatal unit admissions. “ (Clinical manifestations, risk factors, and maternal and perinatal outcomes of coronavirus disease 2019 in pregnancy: living systematic review and meta-analysis

References:

Favre G, Pomar L, Musso D, Baud D. 2019-nCoV epidemic: what about pregnancies? The Lancet 2020; 395(10224).

Chen L, Li Q, Zheng D, et al. Clinical Characteristics of Pregnant Women with Covid-19 in Wuhan, China. New Eng J Med 2020.

Allotey J, Stallings E, Bonet M, et al. Clinical manifestations, risk factors, and maternal and perinatal outcomes of coronavirus disease 2019 in pregnancy: living systematic review and meta-analysis. BMJ 2020;370:m3320