Cancer Treatment Today

Discrepancies between different NGS tests are thought to be due to technical factors, and it is not known whether actionable mutations are identified to a higher degree when more than one test is performed.

D. Stetson et al, Orthogonal Comparison of Four Plasma NGS Tests With Tumor Suggests Technical Factors are a Major Source of Assay Discordance. JCO Precision Oncology Vol.3, 2019

N. M. Kuderer et al, Comparison of 2 Commercially Available Next-Generation Sequencing Platforms in Oncology. JAMA Oncol. 2017;3(7):996-998

NCCN Biomarker Compendium, 2021