NGS for multiple myeloma – pro
Next generation sequencing is most appropriate for patients who have a cancer in which there are several identified molecular targets that are commonly seen. For other cancers, NGS has a possibility of identifying a mutation that represents a new treatment option, but the odds of this may be very low.
Bolli N, Genuardi E, Ziccheddu B, Martello M, Oliva S, Terragna C. Next-Generation Sequencing for Clinical Management of Multiple Myeloma: Ready for Prime Time? Front Oncol. 2020 Feb 25;10:189.
Ewalt MD, West H, Aisner DL. Next Generation Sequencing—Testing Multiple Genetic Markers at Once. JAMA Oncol. 2019;5(7):1076.
NCCN Multiple Myeloma 2023