Sodium 18 PET scan for prostate cancer – pro
18F sodium fluoride (NaF) is a highly sensitive bone-seeking PET biomarker used in the detection of skeletal metastases, and amy idenftify disease that the less sensitive FDG PET can miss. Society for Nuclear mMedicine says that PET/CT 18 F bone scans may be used to identify skeletal metastases, including localization and determination of the extent of disease. Similarly, it is covered by Medicare.1. Registry data suggests than Its imaging-adjusted impact was similar to that observed with 18F-FDG PET for restaging or suspected recurrence in other cancer types.2We await prospective studies.
1.http://interactive.snm.org/docs/Practice%20Guideline%20NaF%20PET%20V1.1.pdf, Version 1.0, 2010
2. Bruce E. Hill et al, Impact of 18F-Fluoride PET in Patients with Known Prostate Cancer: Initial Results from the National Oncologic PET Registry, J Nucl Med April 1, 2014