Squamous breast cancers: Role for adjuvant therapy? – pro

Localized  squamous cancer of the breast is an unusual and rare type of breast cancer. Overwhelming majority of breasr cancer is adenocarcinoma and onlynabout 5% are other histologic types. for this reason, there is no evidence to support providing adjuvant chemotherapy, witth breast type or squamous type Regimens. There unfortunately are no phase II studies or guidelines that comment on the issue of adjuvant therapy, although some reports note that it was done in selected patients.
B. T. Hennesey et al, Management of Unusual Histological Types of Breast Cancer The Oncologist Sep 1, 2012:1135-1145

Triple negative mixed metaplastic breast carcinoma with squamous and spindle cells in an 84-year-old woman: a rare entity with unclear management strategy and poor prognosis BMJ Case Reports Feb 25, 2012

Breast carcinoma–rare types: review of the literature Ann Oncol Nov 1, 2009:1763-1770

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