he largest series is form Norway by Mongot-castellan et la, which included 112 patients. They concluded: The combination of avatrombopag and fostamatinib has been shown to be effective and safe leading to quick response in the majority of treated patients. More research are needed to confirmthese results.”
Maria Eva Mingot Castellano MD PhD 1, Begoña Pedrote Amador MD 1, Riccardo Tomasello MD 2, Waleed Ghanima, Avatrombopag Plus Fostamatinib Combination Efficacy and Safety in Patients with Immune Thrombocytopenia. Blood Volume 142, Supplement 1, 2 November 2023, Page 2596.
Mingot-Castellano ME, Bastida JM, Ghanima W, Ruiz Sainz E, Nuñez Vazquez R, Pedrote Amador B, Abdel-Kader Martín L, Piquer-Monsonis D, Canaro M. Avatrombopag plus fostamatinib combination as treatment in patients with multirefractory immune thrombocytopenia. Br J Haematol. 2024 Oct;205(4):1551-1555. doi: 10.1111/bjh.19602. Epub 2024 Jun 19. PMID: 38895923.