Taxol to Abraxane switch – pro
There is not much literature on the effectiveness in endometrial cancer cases, where Taxol is not tolerated. ABRAXANE IS USUALLY WELL-TOLERATED, AND A RECENT REVIEW RECOMMENDS USING IT IN THIS SITUATION.
It says: ”
Nab-paclitaxel is well-tolerated with no HSRs observed in this series of patients with prior taxane HSR. Given the important role of taxane therapy in nearly all gynecologic malignancies, administration of nab-paclitaxel should be considered prior to abandoning taxane therapy.”
Maurer K et al, Universal tolerance of nab-paclitaxel for gynecologic malignancies in patients with prior taxane hypersensitivity reactions.J Gynecol Oncol. 2017 Jul;28(4):e38