ThyrGenX – pro
Approximately 15-30% of the 525,000 thyroid FNA’s performed on an annual basis are indeterminate based on standard cytological evaluation, and thus are candidates for ThyGenX. ThyGenX has been validated in a prospective, clinical study involving over 600 patients and has a specificity rate of 89%.
Guidelines from the National Comprehensive Cancer Network (NCCN) indicate that molecular diagnostic approaches may be useful in the evaluation of thyroid FNA samples that are indeterminate to assist in patient management, including identifying patients who are appropriate candidates for surgery and those for whom surveillance is appropriate.
Emmanuel Labourier, Alexander Shifrin, Anne E. Busseniers, Mark A. Lupo, Monique L. Manganelli, Bernard Andruss, Dennis Wylie, and Sylvie Beaudenon-Huibregtse Molecular Testing for miRNA, mRNA, and DNA on Fine-Needle Aspiration Improves the Preoperative Diagnosis of Thyroid Nodules With Indeterminate. The Journal of Clinical Endocrinology & Metabolism2015100:7, 2743-2750.
Shrikant Tamhane and Hossein Gharib, Thyroid nodules update in diagnosis and management. Clinical Diabetes and Endocrinology2 0162:10
NCCN, Thyroid Cancer, 2016